A SECOND LOOK AT THE CRYSTAL STRUCTURES OF DROSOPHILA MELANOGASTER ACETYLCHOLINESTERASE IN COMPLEX WITH TACRINE DERIVATIVES PROVIDES INSIGHTS CONCERNING CATALYTIC INTERMEDIATES AND THE DESIGN OF SPECIFIC INSECTICIDES

A Second Look at the Crystal Structures of Drosophila melanogaster Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides

Over recent decades, crystallographic software for data processing and structure refinement has improved dramatically, resulting in more accurate and detailed crystal structures.It is, therefore, sometimes valuable to have a second look at “old” diffraction data, especially when earlier interpretation of the electron density maps was ra

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Acute Poisonings Admitted to a Tertiary Level Intensive Care Unit in Northern India: Patient Profile and Outcomes

Background: Poisoning is becoming a real health care burden for developing countries like India.An improved knowledge of the patterns of poisonings, as well as Strainer Filter the clinical course and outcomes of these cases can help to formulate better preventive and management strategies.Aim: To study the demographic and clinical profiles of patie

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Preservation of renal function by intensive glycemic control

Sweeper We report the case of a 67-year-old Japanese woman with type 1 diabetes mellitus.At 47 years of age, her hemoglobin A1c (HbA1c) was 10.0%, and she had overt nephropathy.The first renal biopsy yielded a diagnosis of diabetic nephropathy.Intensive glycemic control was initiated and her HbA1c improved to 6.0%.Renal dysfunction showed no progre

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Les sujets intersexes peuvent-ils (se) penser ?

Intersex persons are eclipsed by social myths on hermaphrodism and the third sex.However, some who have politicised themselves Drop In Food Wells are demanding that non-consensual interventions practiced by medicine on them in order to conform their bodies to the male and female norms stop.Aware of this critique, medical professionals who invest th

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